A Survey of Genome Editing Activity for 16 Cas12a Orthologs

© 2019 by The Keio Journal of Medicine. The class 2 CRISPR-Cas endonuclease Cas12a (previously known as Cpf1) offers several advantages over Cas9, including the ability to process its own array and the requirement for just a single RNA guide. These attributes make Cas12a promising for many genome en...

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Bibliographic Details
Main Authors: Zetsche, Bernd (Author), Abudayyeh, Omar O. (Author), Gootenberg, Jonathan S (Author), Scott, David Arthur (Author), Zhang, Feng (Author)
Other Authors: Broad Institute of MIT and Harvard (Contributor), McGovern Institute for Brain Research at MIT (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Harvard University- (Contributor)
Format: Article
Language:English
Published: Keio Journal of Medicine, 2022-01-06T14:32:23Z.
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