Improved Process for the Palladium-Catalyzed C-O Cross-Coupling of Secondary Alcohols
Copyright © 2020 American Chemical Society. An improved protocol for the Pd-catalyzed C-O cross-coupling of secondary alcohols is described. The use of biaryl phosphine L2 as the ligand was key to achieving efficient cross-coupling of (hetero)aryl chlorides with only a 20% molar excess of the alcoho...
Main Authors: | Zhang, Hong (Author), Ruiz-Castillo, Paula (Author), Schuppe, Alexander W. (Author), Buchwald, Stephen L. (Author) |
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Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS),
2022-02-14T18:53:41Z.
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Subjects: | |
Online Access: | Get fulltext |
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