A Dual CuH- and Pd-Catalyzed Stereoselective Synthesis of Highly Substituted 1,3-Dienes

A Dual CuH- and Pd-Catalyzed Stereoselective Synthesis of Highly Substituted 1,3-Dienes

Conjugated dienes are versatile building blocks and prevalent substructures in synthetic chemistry. Herein, we report a method for the stereoselective hydroalkenylation of alkynes, utilizing readily available enol triflates. We leveraged an in situ-generated and geometrically pure vinyl-Cu(I) specie...

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Bibliographic Details
Main Authors:	Hou, Chuan-Jin (Author), Schuppe, Alexander W. (Author), Knippel, James Levi (Author), Ni, Anton Z. (Author), Buchwald, Stephen L. (Author)
Format:	Article
Language:	English
Published:	American Chemical Society (ACS), 2022-02-14T19:51:11Z.
Subjects:	Article
Online Access:	Get fulltext

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