Chemically Modified mocRNAs for Highly Efficient Protein Expression in Mammalian Cells

mRNA has recently been established as a new class of therapeutics, due to its programmability and ability to produce proteins of interest rapidly in vivo. Despite its demonstrated utility, mRNA as a protein expression platform remains limited by its translational capacity and RNA stability. Here, we...

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Main Authors: Aditham, Abhishek (Author), Shi, Hailing (Author), Guo, Jianting (Author), Zeng, Hu (Author), Zhou, Yiming (Author), Wade, Sarah Dunn (Author), Huang, Jiahao (Author), Liu, Jia (Author), Wang, Xiao (Author)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2022-03-21T13:32:09Z.
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