Dual modes of CRISPR-associated transposon homing

Tn7-like transposons have co-opted CRISPR systems, including class 1 type I-F, I-B, and class 2 type V-K. Intriguingly, although these CRISPR-associated transposases (CASTs) undergo robust CRISPR RNA (crRNA)-guided transposition, they are almost never found in sites targeted by the crRNAs encoded by...

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Bibliographic Details
Main Authors: Saito, Makoto (Author), Ladha, Alim (Author), Strecker, Jonathan (Author), Faure, Guilhem (Author), Neumann, Edwin (Author), Altae-Tran, Han (Author), Macrae, Rhiannon K. (Author), Zhang, Feng (Author)
Format: Article
Language:English
Published: Elsevier BV, 2022-05-16T19:19:43Z.
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