Highly sensitive Curcumin-conjugated nanotheranostic platform for detecting amyloid-beta plaques by magnetic resonance imaging and reversing cognitive deficits of Alzheimer's disease via NLRP3-inhibition

Highly sensitive Curcumin-conjugated nanotheranostic platform for detecting amyloid-beta plaques by magnetic resonance imaging and reversing cognitive deficits of Alzheimer's disease via NLRP3-inhibition

Abstract Background Alzheimer's disease (AD) is the most common neurodegenerative disorder without effective therapy and lack diagnosis strategy for preclinical AD patients. There is an urgent need for development of both early diagnosis and therapeutic intervention of AD. Results Herein, we de...

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Main Authors: Ruan, Yuting (Author), Xiong, Ying (Author), Fang, Wenli (Author), Yu, Qun (Author), Mai, Yingren (Author), Cao, Zhiyu (Author), Wang, Kexi (Author), Lei, Ming (Author), Xu, Jiaxin (Author), Liu, Yan (Author), Zhang, Xingcai (Author), Liao, Wang (Author), Liu, Jun (Author)
Format: Article
Language:English
Published: BioMed Central, 2022-07-18T12:06:31Z.
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