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|a dc
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|a Naeser, Margaret A.
|e author
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|a Harvard University-
|e contributor
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|a Hamblin, Michael R.
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|a Hamblin, Michael R.
|e contributor
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|a Saltmarche, Anita
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|a Krengel, Maxine H.
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|a Hamblin, Michael R.
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|a Knight, Jeffrey A.
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|a Transcranial LED therapy for cognitive dysfunction in chronic, mild traumatic brain injury: Two case reports
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|b Society of Photo-optical Instrumentation Engineers,
|c 2010-09-15T20:25:09Z.
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|z Get fulltext
|u http://hdl.handle.net/1721.1/58558
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|a Two chronic, traumatic brain injury (TBI) cases are presented, where cognitive function improved following treatment with transcranial light emitting diodes (LEDs). At age 59, P1 had closed-head injury from a motor vehicle accident (MVA) without loss of consciousness and normal MRI, but unable to return to work as development specialist in internet marketing, due to cognitive dysfunction. At 7 years post-MVA, she began transcranial LED treatments with cluster heads (2.1" diameter with 61 diodes each - 9x633nm, 52x870nm; 12-15mW per diode; total power, 500mW; 22.2 mW/cm2) on bilateral frontal, temporal, parietal, occipital and midline sagittal areas (13.3 J/cm2 at scalp, estimated 0.4 J/cm2 to brain cortex per area). Prior to transcranial LED, focused time on computer was 20 minutes. After 2 months of weekly, transcranial LED treatments, increased to 3 hours on computer. Performs nightly home treatments (now, 5 years, age 72); if stops treating >2 weeks, regresses. P2 (age 52F) had history of closed-head injuries related to sports/military training and recent fall. MRI shows fronto-parietal cortical atrophy. Pre-LED, was not able to work for 6 months and scored below average on attention, memory and executive function. Performed nightly transcranial LED treatments at home (9 months) with similar LED device, on frontal and parietal areas. After 4 months of LED treatments, returned to work as executive consultant, international technology consulting firm. Neuropsychological testing (post- 9 months of transcranial LED) showed significant improvement in memory and executive functioning (range, +1 to +2 SD improvement). Case 2 reported reduction in PTSD symptoms.
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|a en_US
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|a Article
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|t Proceedings of the Society of Photo-optical Instrumentation Engineers
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