A plasma signature of human mitochondrial disease revealed through metabolic profiling of spent media from cultured muscle cells
Mutations in either the mitochondrial or nuclear genomes can give rise to respiratory chain disease (RCD), a large class of devastating metabolic disorders. Their clinical management is challenging, in part because we lack facile and accurate biomarkers to aid in diagnosis and in the monitoring of d...
Main Authors: | , , , , , , , , |
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Other Authors: | , |
Format: | Article |
Language: | English |
Published: |
National Academy of Sciences,
2011-02-28T18:09:39Z.
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Subjects: | |
Online Access: | Get fulltext |