Determinants of GBP Recruitment to Toxoplasma gondii Vacuoles and the Parasitic Factors That Control It

Determinants of GBP Recruitment to Toxoplasma gondii Vacuoles and the Parasitic Factors That Control It

IFN-γ is a major cytokine that mediates resistance against the intracellular parasite Toxoplasma gondii. The p65 guanylate-binding proteins (GBPs) are strongly induced by IFN-γ. We studied the behavior of murine GBP1 (mGBP1) upon infection with T. gondii in vitro and confirmed that IFN-γ-dependent r...

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Bibliographic Details
Main Authors: Caradonna, Kacey (Author), Burleigh, Barbara A. (Author), Winter, Sebastian Virreira (Contributor), Niedelman, Wendy Leah (Contributor), Rosowski, Emily Elizabeth (Contributor), Julien, Lindsay (Contributor), Spooner, Eric (Contributor), Saeij, Jeroen (Contributor), Ploegh, Hidde (Contributor), Frickel, Eva-Maria (Contributor), Jensen, Kirk D. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Jensen, Kirk D. C. (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2012-02-15T18:51:21Z.
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