Nonlinear optical microscopy: use of second harmonic generation and two-photon microscopy for automated quantitative liver fibrosis studies
Liver fibrosis is associated with an abnormal increase in an extracellular matrix in chronic liver diseases. Quantitative characterization of fibrillar collagen in intact tissue is essential for both fibrosis studies and clinical applications. Commonly used methods, histological staining followed by...
Main Authors: | Sun, Wanxin (Author), Chang, Shi (Author), Tai, Dean C. S. (Author), Tan, Nancy (Author), Xiao, Guangfa (Author), Tang, Huihuan (Author), Yu, Hanry (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor) |
Format: | Article |
Language: | English |
Published: |
SPIE - International Society for Optical Engineering,
2012-02-16T17:48:34Z.
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Subjects: | |
Online Access: | Get fulltext |
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