Retinal blood flow measurement with ultrahigh-speed swept-source / Fourier domain optical coherence tomography

Doppler OCT is a functional extension of OCT that provides information on flow in biological tissues. We present a novel approach for total retinal blood flow assessment using ultrahigh speed Doppler OCT. A swept source / Fourier domain OCT system at 1050 nm was used for 3D imaging of the human reti...

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Main Authors: Baumann, Bernhard (Contributor), Potsaid, Benjamin M. (Contributor), Liu, Jonathan Jaoshin (Contributor), Kraus, Martin Franz Georg (Contributor), Huang, David (Author), Hornegger, Joachim (Author), Duker, Jay S. (Author), Fujimoto, James G. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Massachusetts Institute of Technology. Research Laboratory of Electronics (Contributor)
Format: Article
Language:English
Published: SPIE, 2012-08-17T12:51:40Z.
Subjects:
Online Access:Get fulltext
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042 |a dc 
100 1 0 |a Baumann, Bernhard  |e author 
100 1 0 |a Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science  |e contributor 
100 1 0 |a Massachusetts Institute of Technology. Research Laboratory of Electronics  |e contributor 
100 1 0 |a Fujimoto, James G.  |e contributor 
100 1 0 |a Baumann, Bernhard  |e contributor 
100 1 0 |a Potsaid, Benjamin M.  |e contributor 
100 1 0 |a Liu, Jonathan Jaoshin  |e contributor 
100 1 0 |a Kraus, Martin Franz Georg  |e contributor 
100 1 0 |a Fujimoto, James G.  |e contributor 
700 1 0 |a Potsaid, Benjamin M.  |e author 
700 1 0 |a Liu, Jonathan Jaoshin  |e author 
700 1 0 |a Kraus, Martin Franz Georg  |e author 
700 1 0 |a Huang, David  |e author 
700 1 0 |a Hornegger, Joachim  |e author 
700 1 0 |a Duker, Jay S.  |e author 
700 1 0 |a Fujimoto, James G.  |e author 
245 0 0 |a Retinal blood flow measurement with ultrahigh-speed swept-source / Fourier domain optical coherence tomography 
260 |b SPIE,   |c 2012-08-17T12:51:40Z. 
856 |z Get fulltext  |u http://hdl.handle.net/1721.1/72180 
520 |a Doppler OCT is a functional extension of OCT that provides information on flow in biological tissues. We present a novel approach for total retinal blood flow assessment using ultrahigh speed Doppler OCT. A swept source / Fourier domain OCT system at 1050 nm was used for 3D imaging of the human retina. The high axial scan rate of 200 kHz allowed measuring the high flow velocities in the central retinal vessels. By analyzing en-face images extracted from 3D Doppler data sets, absolute flow for single vessels as well as total retinal blood flow can be measured using a simple and robust protocol. 
520 |a National Institutes of Health (U.S.) (NIH R01-EY011289-23) 
520 |a National Institutes of Health (U.S.) (R01-EY013178-09) 
520 |a National Institutes of Health (U.S.) (R01-EY013516-07) 
520 |a National Institutes of Health (U.S.) (R01- EY019029-02) 
520 |a United States. Air Force Office of Scientific Research (AFOSR FA9550-07-1-0014) 
520 |a United States. Dept. of Defense. Medical Free Electron Laser Program (FA9550-07-1-0101) 
520 |a Deutsche Forschungsgemeinschaft (DFG) (DFG-GSC80-SAOT) 
546 |a en_US 
655 7 |a Article 
773 |t Proceedings of SPIE--the International Society for Optical Engineering; v. 7885