InAs(ZnCdS) Quantum Dots Optimized for Biological Imaging in the Near-Infrared

We present the synthesis of InAs quantum dots (QDs) with a ZnCdS shell with bright and stable emission in the near-infrared (NIR, 700−900 nm) region for biological imaging applications. We demonstrate how NIR QDs can image tumor vasculature in vivo at significantly deeper penetration depths and with...

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Bibliographic Details
Main Authors: Allen, Peter M. (Contributor), Liu, Wenhao (Contributor), Chauhan, Vikash P. (Author), Lee, Jungmin (Contributor), Ting, Alice Y. (Contributor), Fukumura, Dai (Author), Jain, Rakesh K. (Author), Bawendi, Moungi G. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: American Chemical Society, 2012-10-05T15:38:46Z.
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Online Access:Get fulltext
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042 |a dc 
100 1 0 |a Allen, Peter M.  |e author 
100 1 0 |a Massachusetts Institute of Technology. Department of Chemistry  |e contributor 
100 1 0 |a Bawendi, Moungi G.  |e contributor 
100 1 0 |a Bawendi, Moungi G.  |e contributor 
100 1 0 |a Allen, Peter M.  |e contributor 
100 1 0 |a Liu, Wenhao  |e contributor 
100 1 0 |a Lee, Jungmin  |e contributor 
100 1 0 |a Ting, Alice Y.  |e contributor 
700 1 0 |a Liu, Wenhao  |e author 
700 1 0 |a Chauhan, Vikash P.  |e author 
700 1 0 |a Lee, Jungmin  |e author 
700 1 0 |a Ting, Alice Y.  |e author 
700 1 0 |a Fukumura, Dai  |e author 
700 1 0 |a Jain, Rakesh K.  |e author 
700 1 0 |a Bawendi, Moungi G.  |e author 
245 0 0 |a InAs(ZnCdS) Quantum Dots Optimized for Biological Imaging in the Near-Infrared 
260 |b American Chemical Society,   |c 2012-10-05T15:38:46Z. 
856 |z Get fulltext  |u http://hdl.handle.net/1721.1/73651 
520 |a We present the synthesis of InAs quantum dots (QDs) with a ZnCdS shell with bright and stable emission in the near-infrared (NIR, 700−900 nm) region for biological imaging applications. We demonstrate how NIR QDs can image tumor vasculature in vivo at significantly deeper penetration depths and with higher contrast than visible emitting CdSe(CdS) QDs. Targeted cellular labeling is also presented and may enable multiplexed and low autofluorescence cellular imaging. 
520 |a National Cancer Institute (U.S.) (Grant no. R01-CA085140) 
520 |a National Cancer Institute (U.S.) (Grant no. R01-CA115767) 
520 |a National Cancer Institute (U.S.) (Grant no. R01-CA126642) 
520 |a National Cancer Institute (U.S.) (Grant no. P01-CA080124) 
520 |a National Institutes of Health (U.S.) (MIT-Harvard NIH Center for Cancer Nanotechnology Excellence (1U54-CA119349)) 
520 |a Massachusetts Institute of Technology. Institute for Soldier Nanotechnologies (W911NF-07-D-0004) 
520 |a National Science Foundation (U.S.). Materials Research Science and Engineering Centers (Program) (DMR-0117795) 
546 |a en_US 
655 7 |a Article 
773 |t Journal of the American Chemical Society