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|a dc
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|a Sidorov, Michael Samuel
|e author
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|a Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
|e contributor
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|a Picower Institute for Learning and Memory
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|a Sidorov, Michael Samuel
|e contributor
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|a Auerbach, Benjamin David
|e contributor
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|a Bear, Mark
|e contributor
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|a Auerbach, Benjamin David
|e author
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|a Bear, Mark
|e author
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|a Fragile X mental retardation protein and synaptic plasticity
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|b BioMed Central Ltd,
|c 2013-04-30T19:40:57Z.
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|z Get fulltext
|u http://hdl.handle.net/1721.1/78638
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|a Loss of the translational repressor FMRP causes Fragile X syndrome. In healthy neurons, FMRP modulates the local translation of numerous synaptic proteins. Synthesis of these proteins is required for the maintenance and regulation of long-lasting changes in synaptic strength. In this role as a translational inhibitor, FMRP exerts profound effects on synaptic plasticity.
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|a en
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|a Article
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|t Molecular Brain
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