Polyethylenimine-conjugated gold nanoparticles: Gene transfer potential and low toxicity in the cornea
This study examined the gene transfer efficiency and toxicity of 2-kDa polyethylenimine conjugated to gold nanoparticles (PEI2-GNPs) in the human cornea in vitro and rabbit cornea in vivo. PEI2-GNPs with nitrogen-to-phosphorus ratios of up to 180 exhibited significant transgene delivery in the human...
Main Authors: | , , , , , , , , , |
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Other Authors: | , |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2013-11-15T16:55:01Z.
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Subjects: | |
Online Access: | Get fulltext |