Redox-Linked Structural Changes in Ribonucleotide Reductase
Ribonucleotide reductase (RNR) catalyzes the reduction of ribonucleotides to deoxyribonucleotides. Class I RNRs are composed of two homodimeric proteins, α2 and β2. The class Ia E. coli β2 contains dinuclear, antiferromagnetically coupled iron centers and one tyrosyl free radical, Y122•/β2. Y122• ac...
Main Authors: | Offenbacher, Adam R. (Author), Vassiliev, I. R. (Author), Barry, Bridgette A. (Author), Stubbe, JoAnne (Contributor), Seyedsayamdost, Mohammad R. (Author) |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Seyedsayamdost, M. R. (Contributor) |
Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS),
2013-11-22T20:38:31Z.
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
Redox-Linked Changes to the Hydrogen-Bonding Network of Ribonucleotide Reductase β2
by: Offenbacher, Adam R., et al.
Published: (2015) -
Use of 3-Aminotyrosine To Examine the Pathway Dependence of Radical Propagation in Escherichia coli Ribonucleotide Reductase
by: Minnihan, Ellen Catherine, et al.
Published: (2013) -
Kinetics of radical intermediate formation and deoxynucleotide production in 3-aminotyrosine-substituted Escherichia coli ribonucleotide reductases
by: Minnihan, Ellen Catherine, et al.
Published: (2012) -
Protein structural changes and tyrosyl radical-mediated electron transfer reactions in ribonucleotide reductase and model compounds
by: Offenbacher, Adam R.
Published: (2011) -
Use of 2,3,5-F[subscript 3]Y-beta 2 and 3-NH[subscript 2]Y-alpha 2 To Study Proton-Coupled Electron Transfer in Escherichia coli Ribonucleotide Reductase
by: Seyedsayamdost, Mohammad R., et al.
Published: (2012)