A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity

A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity

Histone modifications are now well-established mediators of transcriptional programs that distinguish cell states. However, the kinetics of histone modification and their role in mediating rapid, signal-responsive gene expression changes has been little studied on a genome-wide scale. Vascular endot...

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Bibliographic Details
Main Authors: Day, Daniel Sindt (Contributor), Park, Peter J. (Contributor), Zhang, Bing (Author), Ho, Joshua W. K. (Author), Song, Lingyun (Author), Cao, Jingjing (Author), Christdoulou, Danos (Author), Seidman, Jonathan G. (Author), Crawford, Gregory E. (Author), Pu, William T. (Author)
Other Authors: Whitaker College of Health Sciences and Technology (Contributor), Harvard University- (Contributor)
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory Press, 2013-12-13T15:45:59Z.
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