Efficient measurement of total tumor microvascularity ex vivo using a mathematical model to optimize volume subsampling
We introduce immunofluorescence and automated image processing protocols for serial tumor sections to objectively and efficiently quantify tumor microvasculature following antivascular therapy. To determine the trade-off between tumor subsampling and throughput versus microvessel quantification accu...
Main Authors: | Spring, Bryan Q. (Author), Palanisami, Akilan (Author), Zheng, Lei Zak (Author), Blatt, Amy E. (Author), Bryan Sears, R. (Author), Hasan, Tayyaba (Contributor) |
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Other Authors: | Harvard University- (Contributor) |
Format: | Article |
Language: | English |
Published: |
SPIE,
2013-12-23T18:34:23Z.
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Subjects: | |
Online Access: | Get fulltext |
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