Prospective identification of parasitic sequences in phage display screens
Phage display empowered the development of proteins with new function and ligands for clinically relevant targets. In this report, we use next-generation sequencing to analyze phage-displayed libraries and uncover a strong bias induced by amplification preferences of phage in bacteria. This bias fav...
Main Authors: | Li, Shuo C. (Contributor), Matochko, Wadim L. (Author), Tang, Sindy K. Y. (Author), Derda, Ratmir (Author) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering (Contributor) |
Format: | Article |
Language: | English |
Published: |
Oxford University Press,
2013-12-23T20:01:02Z.
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Subjects: | |
Online Access: | Get fulltext |
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