Evolutionary remodeling of global regulatory networks during long-term bacterial adaptation to human hosts
The genetic basis of bacterial adaptation to a natural environment has been investigated in a highly successful Pseudomonas aeruginosa lineage (DK2) that evolved within the airways of patients with cystic fibrosis (CF) for more than 35 y. During evolution in the CF airways, the DK2 lineage underwent...
Main Authors: | Yang, Lei (Contributor), Damkiaer, Soren (Author), Molin, Soren (Author), Jelsbak, Lars (Author) |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering (Contributor) |
Format: | Article |
Language: | English |
Published: |
National Academy of Sciences (U.S.),
2013-12-30T15:36:55Z.
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
Bacterial adaptation during chronic infection revealed by independent component analysis of transcriptomic data
by: Molin Søren, et al.
Published: (2011-08-01) -
Genome analysis of a transmissible lineage of pseudomonas aeruginosa reveals pathoadaptive mutations and distinct evolutionary paths of hypermutators.
by: Rasmus Lykke Marvig, et al.
Published: (2013-01-01) -
The evolution of antimicrobial peptide resistance in Pseudomonas aeruginosa is shaped by strong epistatic interactions
by: Nicholas Jochumsen, et al.
Published: (2016-10-01) -
Bacterial persisters in long-term infection: Emergence and fitness in a complex host environment.
by: Jennifer A Bartell, et al.
Published: (2020-12-01) -
Evolutionary Remodeling of Bacterial Motility Checkpoint Control
by: Bin Ni, et al.
Published: (2017-01-01)