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84702 |
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|a dc
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|a Zhang, L.
|e author
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|a Massachusetts Institute of Technology. Department of Biology
|e contributor
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|a Whitehead Institute for Biomedical Research
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|a Zhang, L.
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|a Sankaran, V. G.
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|a Lodish, Harvey F.
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|a Sankaran, Vijay G.
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|a Lodish, Harvey F
|e author
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|a MicroRNAs in erythroid and megakaryocytic differentiation and megakaryocyte-erythroid progenitor lineage commitment
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|b Nature Publishing Group,
|c 2014-02-07T20:00:04Z.
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|z Get fulltext
|u http://hdl.handle.net/1721.1/84702
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|a MicroRNAs (miRNAs) are a class of small regulatory noncoding RNAs that modulate the expression of their target genes through either mRNA degradation or inhibition of protein translation. In recent years, miRNAs have been shown to be critical regulators of hematopoiesis and have important roles in the differentiation of specific lineages. Here, we summarize our current understanding of miRNAs involved in hematopoiesis with a focus on the role of miRNAs in regulating erythroid and megakaryocytic differentiation and megakaryocyte-erythroid progenitor lineage commitment.
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|a Singapore-MIT Alliance for Research and Technology (graduate fellowship)
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|a National Institutes of Health (U.S.) (NIH grant T32HL007574-30)
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|a Boston Children's Hospital. Department of Medicine
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|a Singapore-MIT Alliance for Research and Technology (SMA grant C-382-641-001-091)
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|a National Institutes of Health (U.S.) (NIH grant DK047618)
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|a National Institutes of Health (U.S.) (grant DK068348)
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|a National Institutes of Health (U.S.) (grant 5P01 HL066105)
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|a en_US
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|a Article
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|t Leukemia
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