Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery
Nanoparticle-mediated siRNA delivery is a complex process that requires transport across numerous extracellular and intracellular barriers. As such, the development of nanoparticles for efficient delivery would benefit from an understanding of how parameters associated with these barriers relate to...
Main Authors: | Alabi, Christopher A. (Contributor), Sahay, Gaurav (Contributor), Yin, Hao (Contributor), Luly, Kathryn M. (Author), Anderson, Daniel Griffith (Contributor), Love, Kevin T (Author), Langer, Robert S (Author) |
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Other Authors: | Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Love, Kevin T. (Contributor), Langer, Robert (Contributor) |
Format: | Article |
Language: | English |
Published: |
National Academy of Sciences (U.S.),
2014-08-29T11:50:53Z.
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Subjects: | |
Online Access: | Get fulltext |
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