Comparative Studies of Disordered Proteins with Similar Sequences: Application to Aβ40 and Aβ42

Comparative Studies of Disordered Proteins with Similar Sequences: Application to Aβ40 and Aβ42

Quantitative comparisons of intrinsically disordered proteins (IDPs) with similar sequences, such as mutant forms of the same protein, may provide insights into IDP aggregation-a process that plays a role in several neurodegenerative disorders. Here we describe an approach for modeling IDPs with sim...

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Bibliographic Details
Main Authors: Fisher, Charles K. (Author), Ullman, Orly (Contributor), Stultz, Collin M (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Massachusetts Institute of Technology. Research Laboratory of Electronics (Contributor), Stultz, Collin M. (Contributor)
Format: Article
Language:English
Published: Elsevier B.V., 2014-10-07T15:53:22Z.
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