Kinetic isotope effects significantly influence intracellular metabolite [superscript 13]C labeling patterns and flux determination

Rigorous mathematical modeling of carbon-labeling experiments allows estimation of fluxes through the pathways of central carbon metabolism, yielding powerful information for basic scientific studies as well as for a wide range of applications. However, the mathematical models that have been develop...

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Bibliographic Details
Main Authors: Stephanopoulos, Gregory (Contributor), Wasylenko, Thomas Michael (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor)
Format: Article
Language:English
Published: Wiley Blackwell, 2014-11-07T18:40:17Z.
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