Kinetic isotope effects significantly influence intracellular metabolite [superscript 13]C labeling patterns and flux determination
Rigorous mathematical modeling of carbon-labeling experiments allows estimation of fluxes through the pathways of central carbon metabolism, yielding powerful information for basic scientific studies as well as for a wide range of applications. However, the mathematical models that have been develop...
Main Authors: | Stephanopoulos, Gregory (Contributor), Wasylenko, Thomas Michael (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor) |
Format: | Article |
Language: | English |
Published: |
Wiley Blackwell,
2014-11-07T18:40:17Z.
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Subjects: | |
Online Access: | Get fulltext |
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