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92383 |
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|a dc
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|a Forest, Craig R.
|e author
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|a Massachusetts Institute of Technology. Department of Biological Engineering
|e contributor
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|a Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
|e contributor
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|a Massachusetts Institute of Technology. Media Laboratory
|e contributor
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|a McGovern Institute for Brain Research at MIT
|e contributor
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|a Program in Media Arts and Sciences
|q (Massachusetts Institute of Technology)
|e contributor
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|a Kodandaramaiah, Suhasa Bangalo
|e contributor
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|a Boyden, Edward Stuart
|e contributor
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|a Kodandaramaiah, Suhasa Bangalo
|e author
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|a Boyden, Edward
|e author
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|a In vivo robotics: the automation of neuroscience and other intact-system biological fields
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|b Wiley Blackwell,
|c 2014-12-18T18:10:29Z.
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|z Get fulltext
|u http://hdl.handle.net/1721.1/92383
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|a Robotic and automation technologies have played a huge role in in vitro biological science, having proved critical for scientific endeavors such as genome sequencing and high-throughput screening. Robotic and automation strategies are beginning to play a greater role in in vivo and in situ sciences, especially when it comes to the difficult in vivo experiments required for understanding the neural mechanisms of behavior and disease. In this perspective, we discuss the prospects for robotics and automation to influence neuroscientific and intact-system biology fields. We discuss how robotic innovations might be created to open up new frontiers in basic and applied neuroscience and present a concrete example with our recent automation of in vivo whole-cell patch clamp electrophysiology of neurons in the living mouse brain.
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|a National Institutes of Health (U.S.) (Single Cell Grant 1 R01 EY023173)
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|a Human Frontier Science Program (Strasbourg, France)
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|a McGovern Institute for Brain Research at MIT. Neurotechnology (MINT) Program
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|a MIT Media Lab Consortium
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|a New York Stem Cell Foundation (Robertson Investigator Award)
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|a National Institutes of Health (U.S.) (Director's New Innovator Award 1DP2OD002002)
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|a National Institutes of Health (U.S.) (EUREKA Award 1R01GM104948)
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|a National Institutes of Health (U.S.) (Grant 1R01DA029639)
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|a National Institutes of Health (U.S.) (Grant 1R01NS067199)
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|a National Science Foundation (U.S.) (CAREER Award CBET 1053233)
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|a National Science Foundation (U.S.) (DMS1042134)
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|a Paul G. Allen Family Foundation (Distinguished Investigator in Neuroscience Award)
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|a Skolkovo Institute of Science and Technology
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|a en_US
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|a Article
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|t Annals of the New York Academy of Sciences
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