Mild and General Palladium-Catalyzed Synthesis of Methyl Aryl Ethers Enabled by the Use of a Palladacycle Precatalyst

Mild and General Palladium-Catalyzed Synthesis of Methyl Aryl Ethers Enabled by the Use of a Palladacycle Precatalyst

A general method for the Pd-catalyzed coupling of methanol with (hetero)aryl halides is described. The reactions proceed under mild conditions with a wide range of aryl and heteroaryl halides to give methyl aryl ethers in high yield.

Bibliographic Details
Main Authors: Cheung, Chi Wai (Contributor), Buchwald, Stephen Leffler (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2015-02-06T19:50:40Z.
Subjects:
Article
Online Access:Get fulltext
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100 1 0 |a Cheung, Chi Wai  |e author 
100 1 0 |a Massachusetts Institute of Technology. Department of Chemistry  |e contributor 
100 1 0 |a Cheung, Chi Wai  |e contributor 
100 1 0 |a Buchwald, Stephen Leffler  |e contributor 
700 1 0 |a Buchwald, Stephen Leffler  |e author 
245 0 0 |a Mild and General Palladium-Catalyzed Synthesis of Methyl Aryl Ethers Enabled by the Use of a Palladacycle Precatalyst 
260 |b American Chemical Society (ACS),   |c 2015-02-06T19:50:40Z. 
856 |z Get fulltext  |u http://hdl.handle.net/1721.1/93912 
520 |a A general method for the Pd-catalyzed coupling of methanol with (hetero)aryl halides is described. The reactions proceed under mild conditions with a wide range of aryl and heteroaryl halides to give methyl aryl ethers in high yield. 
520 |a National Institutes of Health (U.S.) (GM58160) 
520 |a Croucher Foundation (Postdoctoral Fellowship) 
546 |a en_US 
655 7 |a Article 
773 |t Organic Letters 

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