Copper-Catalyzed Oxytrifluoromethylation of Unactivated Alkenes

A mild, versatile, and convenient method for the efficient oxytrifluoromethylation of unactivated alkenes based on a copper-catalyzed oxidative difunctionalization strategy has been developed. This methodology provides access to a variety of classes of synthetically useful CF[subscript 3]-containing...

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Bibliographic Details
Main Authors: Zhu, Rong (Contributor), Buchwald, Stephen Leffler (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2015-02-11T15:50:12Z.
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Online Access:Get fulltext
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100 1 0 |a Zhu, Rong  |e author 
100 1 0 |a Massachusetts Institute of Technology. Department of Chemistry  |e contributor 
100 1 0 |a Zhu, Rong  |e contributor 
100 1 0 |a Buchwald, Stephen Leffler  |e contributor 
700 1 0 |a Buchwald, Stephen Leffler  |e author 
245 0 0 |a Copper-Catalyzed Oxytrifluoromethylation of Unactivated Alkenes 
260 |b American Chemical Society (ACS),   |c 2015-02-11T15:50:12Z. 
856 |z Get fulltext  |u http://hdl.handle.net/1721.1/94323 
520 |a A mild, versatile, and convenient method for the efficient oxytrifluoromethylation of unactivated alkenes based on a copper-catalyzed oxidative difunctionalization strategy has been developed. This methodology provides access to a variety of classes of synthetically useful CF[subscript 3]-containing building blocks from simple starting materials. 
520 |a National Institutes of Health (U.S.) (Grant GM46059) 
520 |a Amgen Inc. 
520 |a National Science Foundation (U.S.) (Grant CHE 9808061) 
520 |a National Science Foundation (U.S.) (Grant 9729592) 
520 |a National Institutes of Health (U.S.) (1S10RR13886-01) 
546 |a en_US 
655 7 |a Article 
773 |t Journal of the American Chemical Society