The evolution of drug resistance in clinical isolates of Candida albicans

The evolution of drug resistance in clinical isolates of Candida albicans

Candida albicans is both a member of the healthy human microbiome and a major pathogen in immunocompromised individuals. Infections are typically treated with azole inhibitors of ergosterol biosynthesis often leading to drug resistance. Studies in clinical isolates have implicated multiple mechanism...

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Main Authors: Abbey, Darren A. (Author), Issi, Luca (Author), Guiducci, Candace (Author), Martinez, Diego A (Author), Delorey, Toni (Author), Li, Bi yu (Author), White, Theodore C (Author), Cuomo, Christina (Author), Rao, Reeta P (Author), Berman, Judith (Author), Thompson, Dawn A (Author), Regev, Aviv (Contributor), Ford, Christopher B. (Contributor), Funt, Jason (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: eLife Sciences Publications, Ltd., 2015-02-11T21:27:13Z.
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