The evolution of drug resistance in clinical isolates of Candida albicans
Candida albicans is both a member of the healthy human microbiome and a major pathogen in immunocompromised individuals. Infections are typically treated with azole inhibitors of ergosterol biosynthesis often leading to drug resistance. Studies in clinical isolates have implicated multiple mechanism...
Main Authors: | Abbey, Darren A. (Author), Issi, Luca (Author), Guiducci, Candace (Author), Martinez, Diego A (Author), Delorey, Toni (Author), Li, Bi yu (Author), White, Theodore C (Author), Cuomo, Christina (Author), Rao, Reeta P (Author), Berman, Judith (Author), Thompson, Dawn A (Author), Regev, Aviv (Contributor), Ford, Christopher B. (Contributor), Funt, Jason (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor) |
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications, Ltd.,
2015-02-11T21:27:13Z.
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Subjects: | |
Online Access: | Get fulltext |
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