Encapsulation of Pt(IV) prodrugs within a Pt(II) cage for drug delivery

Encapsulation of Pt(IV) prodrugs within a Pt(II) cage for drug delivery

This report presents a novel strategy that facilitates delivery of multiple, specific payloads of Pt(IV) prodrugs using a well-defined supramolecular system. This delivery system comprises a hexanuclear Pt(II) cage that can host four Pt(IV) prodrug guest molecules. Relying on host-guest interactions...

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Bibliographic Details
Main Authors: Suntharalingam, Kogularamanan (Contributor), Lippard, Stephen J. (Contributor), Zheng, Yaorong (Contributor), Johnstone, Timothy (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry, The, 2015-02-24T20:19:59Z.
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