Redox-Linked Changes to the Hydrogen-Bonding Network of Ribonucleotide Reductase β2

Redox-Linked Changes to the Hydrogen-Bonding Network of Ribonucleotide Reductase β2

Ribonucleotide reductase (RNR) catalyzes conversion of nucleoside diphosphates (NDPs) to 2'-deoxynucleotides, a critical step in DNA replication and repair in all organisms. Class-Ia RNRs, found in aerobic bacteria and all eukaryotes, are a complex of two subunits: α2 and β2. The β2 subunit con...

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Bibliographic Details
Main Authors:	Offenbacher, Adam R. (Author), Minnihan, Ellen Catherine (Contributor), Stubbe, JoAnne (Contributor), Barry, Bridgette A. (Author)
Other Authors:	Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format:	Article
Language:	English
Published:	American Chemical Society (ACS), 2015-02-26T18:02:47Z.
Subjects:	Article
Online Access:	Get fulltext

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