ATP Consumption Promotes Cancer Metabolism
Cancer cells metabolize glucose by aerobic glycolysis, a phenomenon known as the Warburg effect. Fang et al. (2010) show that the endoplasmic reticulum enzyme ENTPD5 promotes ATP consumption and favors aerobic glycolysis. The findings suggest that nutrient uptake in cancer cells is limited by ATP an...
Main Authors: | Israelsen, William James (Contributor), Vander Heiden, Matthew G. (Contributor) |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor) |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2015-03-17T17:22:39Z.
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
Pyruvate kinase: Function, regulation and role in cancer
by: Israelsen, William James, et al.
Published: (2016) -
Targeting cancer metabolism: a therapeutic window opens
by: Vander Heiden, Matthew G.
Published: (2013) -
Acetate metabolism in cancer cells
by: Hosios, Aaron M, et al.
Published: (2014) -
METabolic Adaptations in the Tumor MYCroenvironment
by: Vander Heiden, Matthew G, et al.
Published: (2014) -
Metabolism and Congenital Malformations - NAD's Effects on Development
by: Vander Heiden, Matthew G.
Published: (2018)