Sickle Cell MicroRNAs Inhibit the Malaria Parasite

Sickle cell hemoglobin conveys resistance to malaria. In this issue of Cell Host & Microbe, LaMonte et al. (2012) demonstrate a surprising mechanism for this innate immunity. A microRNA enriched in sickle red blood cells is translocated into the parasite, incorporated covalently into P. falcipar...

Full description

Bibliographic Details
Main Authors: Duraisingh, Manoj T (Author), Lodish, Harvey F (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Lodish, Harvey F. (Contributor)
Format: Article
Language:English
Published: Elsevier B.V., 2015-03-30T20:43:25Z.
Subjects:
Online Access:Get fulltext
LEADER 01085 am a22002053u 4500
001 96269
042 |a dc 
100 1 0 |a Duraisingh, Manoj T.  |e author 
100 1 0 |a Massachusetts Institute of Technology. Department of Biological Engineering  |e contributor 
100 1 0 |a Massachusetts Institute of Technology. Department of Biology  |e contributor 
100 1 0 |a Whitehead Institute for Biomedical Research  |e contributor 
100 1 0 |a Lodish, Harvey F.  |e contributor 
700 1 0 |a Lodish, Harvey F  |e author 
245 0 0 |a Sickle Cell MicroRNAs Inhibit the Malaria Parasite 
260 |b Elsevier B.V.,   |c 2015-03-30T20:43:25Z. 
856 |z Get fulltext  |u http://hdl.handle.net/1721.1/96269 
520 |a Sickle cell hemoglobin conveys resistance to malaria. In this issue of Cell Host & Microbe, LaMonte et al. (2012) demonstrate a surprising mechanism for this innate immunity. A microRNA enriched in sickle red blood cells is translocated into the parasite, incorporated covalently into P. falciparum mRNAs and inhibits parasite growth. 
546 |a en_US 
655 7 |a Article 
773 |t Cell Host & Microbe