Next-generation sequencing reveals the biological significance of the N[superscript 2],3-ethenoguanine lesion in vivo

Next-generation sequencing reveals the biological significance of the N[superscript 2],3-ethenoguanine lesion in vivo

Etheno DNA adducts are a prevalent type of DNA damage caused by vinyl chloride (VC) exposure and oxidative stress. Etheno adducts are mutagenic and may contribute to the initiation of several pathologies; thus, elucidating the pathways by which they induce cellular transformation is critical. Althou...

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Main Authors: Chang, Shiou-chi (Contributor), Wu, Jie (Contributor), Delaney, James C. (Contributor), Li, Deyu (Contributor), Zhao, Linlin (Author), Christov, Plamen P. (Author), Yau, Emily (Contributor), Singh, Vipender (Contributor), Jost, Marco (Author), Marnett, Lawrence J. (Author), Rizzo, Carmelo J. (Author), Levine, Stuart S. (Contributor), Guengerich, F. Peter (Author), Essigmann, John M. (Contributor), Drennan, Catherine L (Author), Fedeles, Bogdan I (Author)
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Drennan, Catherine L. (Contributor), Fedeles, Bogdan I. (Contributor)
Format: Article
Language:English
Published: Oxford University Press, 2015-04-08T16:21:52Z.
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