Evaluating the sensitivity of hybridization-based epigenotyping using a methyl binding domain protein

Hypermethylation of CpG islands in gene promoter regions has been shown to be a predictive biomarker for certain diseases. Most current methods for methylation profiling are not well-suited for clinical analysis. Here, we report the development of an inexpensive device and an epigenotyping assay wit...

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Bibliographic Details
Main Authors: Shatova, Tatyana A. (Contributor), Lee, Jungkyu K. (Author), Kaastrup, Kaja (Contributor), Heimer, Brandon Walter (Contributor), Sikes, Hadley (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry, 2015-05-04T14:45:16Z.
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