Oxygen levels in thermoplastic microfluidic devices during cell culture

We developed a computational model to predict oxygen levels in microfluidic plastic devices during cell culture. This model is based on experimental evaluation of oxygen levels. Conditions are determined that provide adequate oxygen supply to two cell types, hepatocytes and endothelial cells, either...

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Bibliographic Details
Main Authors: Ochs, Christopher J. (Author), Kasuya, Junichi (Contributor), Pavesi, Andrea (Author), Kamm, Roger Dale (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry, 2015-06-22T18:50:23Z.
Subjects:
Online Access:Get fulltext
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100 1 0 |a Ochs, Christopher J.  |e author 
100 1 0 |a Massachusetts Institute of Technology. Department of Biological Engineering  |e contributor 
100 1 0 |a Kasuya, Junichi  |e contributor 
100 1 0 |a Kamm, Roger Dale  |e contributor 
700 1 0 |a Kasuya, Junichi  |e author 
700 1 0 |a Pavesi, Andrea  |e author 
700 1 0 |a Kamm, Roger Dale  |e author 
245 0 0 |a Oxygen levels in thermoplastic microfluidic devices during cell culture 
260 |b Royal Society of Chemistry,   |c 2015-06-22T18:50:23Z. 
856 |z Get fulltext  |u http://hdl.handle.net/1721.1/97509 
520 |a We developed a computational model to predict oxygen levels in microfluidic plastic devices during cell culture. This model is based on experimental evaluation of oxygen levels. Conditions are determined that provide adequate oxygen supply to two cell types, hepatocytes and endothelial cells, either by diffusion through the plastic device, or by supplying a low flow rate of medium. 
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655 7 |a Article 
773 |t Lab on a Chip