Colitis and Colon Cancer in WASP-Deficient Mice Require Helicobacter Spp.

Colitis and Colon Cancer in WASP-Deficient Mice Require Helicobacter Spp.

Background: Wiskott-Aldrich syndrome protein-deficient patients and mice are immunodeficient and can develop inflammatory bowel disease. The intestinal microbiome is critical to the development of colitis in most animal models, in which Helicobacter spp. have been implicated in disease pathogenesis....

Full description

Bibliographic Details
Main Authors: Nguyen, Deanna D. (Author), Goettel, Jeremy A. (Author), Eston, Michelle A. (Author), Mobley, Melissa W. (Contributor), Taylor, Nancy S. (Contributor), McCabe, Amanda F. (Contributor), Marin, Romela (Author), Snapper, Scott B. (Author), Fox, James G. (Contributor), Muthupalani, Sureshkumar (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Division of Comparative Medicine (Contributor)
Format: Article
Language:English
Published: Lippincott Williams & Wilkins, 2015-10-20T12:56:42Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items