An efficient system for the Pd-catalyzed cross-coupling of amides and aryl chlorides
A catalyst based on a new biarylphosphine ligand (3) for the Pd-catalyzed cross-coupling reactions of amides and aryl chlorides is described. This system shows the highest turnover frequencies reported to date for these reactions, especially for aryl chloride substrates bearing an ortho substituent....
Main Authors: | Fors, Brett P. (Contributor), Dooleweerdt, Karin (Contributor), Zeng, Qingle (Contributor), Buchwald, Stephen Leffler (Contributor) |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Chemistry (Contributor) |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2015-10-28T12:51:22Z.
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
Pd-Catalyzed Cross-Coupling Reactions of Amides and Aryl Mesylates
by: Dooleweerdt, Karin, et al.
Published: (2012) -
Pd-Catalyzed Conversion of Aryl Chlorides, Triflates, and Nonaflates to Nitroaromatics
by: Fors, Brett P., et al.
Published: (2013) -
Simple, efficient protocols for the Pd-catalyzed cross-coupling reaction of aryl chlorides and dimethylamine
by: Lee, Brian K., et al.
Published: (2015) -
An Efficient Process for Pd-Catalyzed C−N Cross-Coupling Reactions of Aryl Iodides: Insight Into Controlling Factors
by: Fors, Brett P., et al.
Published: (2013) -
Palladium-Catalyzed Cross-Coupling of Aryl Chlorides and Triflates with Sodium Cyanate: A Practical Synthesis of Unsymmetrical Ureas
by: Fors, Brett P., et al.
Published: (2013)