Identification of signaling pathways related to drug efficacy in hepatocellular carcinoma via integration of phosphoproteomic, genomic and clinical data
Hepatocellular Carcinoma (HCC) is one of the leading causes of death worldwide, with only a handful of treatments effective in unresectable HCC. Most of the clinical trials for HCC using new generation interventions (drug-targeted therapies) have poor efficacy whereas just a few of them show some pr...
Main Authors: | Melas, Ioannis N. (Author), Lauffenburger, Douglas A. (Contributor), Alexopoulos, Leonidas G. (Author) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering (Contributor) |
Format: | Article |
Language: | English |
Published: |
Institute of Electrical and Electronics Engineers (IEEE),
2015-10-29T13:44:38Z.
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Subjects: | |
Online Access: | Get fulltext |
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