Prostaglandin-E2 is produced by adult human epidermal melanocytes in response to UVB in a melanogenesis-independent manner.

Prostaglandin-E2 is produced by adult human epidermal melanocytes in response to UVB in a melanogenesis-independent manner.

no === Erythema occurs in human skin following excessive exposure to ultraviolet radiation (UVR), and this is in part mediated by the vasodilator prostaglandin E2 (PGE2). While keratinocytes are a major source of this pro-inflammatory eicosanoid, epidermal melanocytes (EM) also express some of the c...

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Bibliographic Details
Main Authors: Gledhill, Karl, Rhodes, L.E., Brownrigg, M., Haylett, A.K., Masoodi, Mojgan, Thody, Anthony J., Nicolaou, Anna, Tobin, Desmond J.
Language:en
Published: Wiley 2010
Subjects:
Epidermal melanocyte
Ultraviolet radiation (UVR)
Prostaglandin E2
Cyclooxygenase
Dopachrome tautomerase
Melanogenesis
Skin phototype
Erythema
Online Access:http://hdl.handle.net/10454/4579

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