The effects of the deregulated expression of the cloned transcription factor E2F-1 on Chinese hamster ovary cells
E2F-1 is one of a family of transcription factors known to be involved in cell cycle regulation at the G1/S phase transition. Several proteins intimately involved in DNA synthesis are regulated by the E2F-1 transcription factor family. It is believed that the presence of free E2F-1 in mammalian cell...