Progress towards the total synthesis of a spermine-conjugated dynemicin analog
Progress towards the synthesis of the spermine-conjugated Dynemicin analog 4 is described. The synthetic route starts with the Michael addition of menthyl acetoacetate to trans-ethyl crotonate followed by a Dieckman condensation to form the cyclohexanedione 14 which, through a series of chemical...
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| Format: | Others |
| Language: | en |
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1998
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| Online Access: | https://thesis.library.caltech.edu/7932/1/Hoang_bh_1998.pdf Hoang, Bac H. (1998) Progress towards the total synthesis of a spermine-conjugated dynemicin analog. Master's thesis, California Institute of Technology. doi:10.7907/3g9z-nn03. https://resolver.caltech.edu/CaltechTHESIS:08222013-144438603 <https://resolver.caltech.edu/CaltechTHESIS:08222013-144438603> |