A Mathematical Model of the Effect of Aspirin on Blood Clotting
In this paper, we provide a mathematical model of the effect of aspirin on blood clotting. The model tracks the enzyme prostaglandin H synthase and an important blood clotting factor, thromboxane A2, in the form of thromboxane B2. Through model analysis, we determine conditions under which the react...
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| Format: | Others |
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Scholarship @ Claremont
2015
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| Online Access: | http://scholarship.claremont.edu/scripps_theses/718 http://scholarship.claremont.edu/cgi/viewcontent.cgi?article=1631&context=scripps_theses |
| Summary: | In this paper, we provide a mathematical model of the effect of aspirin on blood clotting. The model tracks the enzyme prostaglandin H synthase and an important blood clotting factor, thromboxane A2, in the form of thromboxane B2. Through model analysis, we determine conditions under which the reactions of prostaglandin H synthase are self-sustaining. Lastly, through numerical simulations, we demonstrate that the model accurately captures the steady-state chemical concentrations of interest in blood, both with and without aspirin treatment. |
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