Mechanisms by Which Guanylate Binding Proteins Target Pathogen Vacuoles and Promote Caspase-11 Dependent Pyroptosis
<p>Guanylate binding proteins (Gbps) are a family of large GTPases that are highly stimulated by IFNγ and confer resistance to various viral, protozoan, and bacterial pathogens. Following infections of intracellular pathogens, multiple Gbps can localize to pathogen vacuoles and promote the ve...
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2015
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| Online Access: | http://hdl.handle.net/10161/11369 |