Development of a beta-Secretase Activated Prochelator and FRET Probe to Mediate Copper Toxicity in Alzheimer's Disease
<p>Alzheimer's disease (AD) is a progressive neurodegenerative disease that affects over 5 million people in the United States alone. This number is predicted to triple to by the year 2050 due to both increasing life expectancies and the absence of disease-attenuating drugs. The etiology...
Main Author: | Folk, Drew Steven |
---|---|
Other Authors: | Franz, Katherine J |
Published: |
2012
|
Subjects: | |
Online Access: | http://hdl.handle.net/10161/5825 |
Similar Items
-
Planejamento racional de inibidores da beta-secretase em mal de Alzheimer
by: Evandro Pizeta Semighini
Published: (2013) -
Planejamento racional de inibidores da beta-secretase em mal de Alzheimer
by: Semighini, Evandro Pizeta
Published: (2013) -
The amyloid-beta forming tripeptide cleavage mechanism of γ-secretase
by: David M Bolduc, et al.
Published: (2016-08-01) -
Comparative Interactome Investigation of γ-secretase Complex in Alzheimer’s Disease
by: Jeon, Amy Hye Won
Published: (2012) -
Comparative Interactome Investigation of γ-secretase Complex in Alzheimer’s Disease
by: Jeon, Amy Hye Won
Published: (2012)