S100A9 Sustains Myeloid-Derived Suppressor Expansion and Immunosuppression During Chronic Murine Sepsis

S100A9 Sustains Myeloid-Derived Suppressor Expansion and Immunosuppression During Chronic Murine Sepsis

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Myeloid-derived suppressor cells (MDSC) expand during sepsis, suppress both innate and adaptive immunity, and promote chronic immunosuppression, which characterizes the late/chronic phase of sepsis. We previously reported that the transcription factors Stat3 and C/EBPb synergize to induces the expre...

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Bibliographic Details
Main Authors: Alkhateeb, Tuqa, PharmD, Kumbhare, Ajinkya, MD, Bah, Isatou, BS, Elgazzar, Mohamed, PhD
Published: Digital Commons @ East Tennessee State University 2019
Subjects:
sepsis
MDSCs
immunosuppression
S100A9
Immune System
Bacterial Infections
Infectious Diseases
Inflammation
Critical Care
Online Access:https://dc.etsu.edu/asrf/2019/schedule/217

Internet

https://dc.etsu.edu/asrf/2019/schedule/217

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