Engineering ligand-receptor pairs for small molecule control of transcription

Creating receptors for control of transcription with arbitrary small molecules has widespread applications including gene therapy, biosensors, and enzyme engineering. Using the combination of high throughput docking, codon randomization, and chemical complementation, we have created new receptors...

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Bibliographic Details
Main Author: Schwimmer, Lauren J.
Format: Others
Language:en_US
Published: Georgia Institute of Technology 2006
Subjects:
Online Access:http://hdl.handle.net/1853/11651

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