Reciprocal binding of sphingosine and phosphatidic acid to steroidogenic factor 1 regulates the transcription of CYP17
Steroidogenic factor (SF1) is an orphan nuclear receptor that is essential for steroid hormone-biosynthesis and endocrine development. Recent studies have demonstrated that phospholipids are ligands for SF1. In the present study our aim was to identify endogenous ligands for SF1 and characterize t...
Main Author: | Urs, Aarti N. |
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Format: | Others |
Language: | en_US |
Published: |
Georgia Institute of Technology
2006
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Subjects: | |
Online Access: | http://hdl.handle.net/1853/7638 |
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