Avalia??o de protocolos de cintilografia renal com 99mTc-DMSA em crian?as com suspeita cl?nica de pielonefrite aguda

• Main Author: Vilas, Eduardo Rosito de
• Other Authors: Baldisserotto, Matteo
• Format: Others
• Language: Portuguese
• Published: Pontif?cia Universidade Cat?lica do Rio Grande do Sul 2015
• Subjects: MEDICINA; MEDICINA NUCLEAR; PEDIATRIA; INFEC??ES URIN?RIAS; RADIOFARMAC?UTICA; CLINICA MEDICA::PEDIATRIA
• Online Access: http://tede2.pucrs.br/tede2/handle/tede/6025

Submitted by Setor de Tratamento da Informa??o - BC/PUCRS ([e-mail]) on 2015-05-18T12:11:50Z No. of bitstreams: 1 468781 - Texto Parcial.pdf: 384702 bytes, checksum: cde465ffd6e2d42c31965ab814bea74f (MD5) === Made available in DSpace on 2015-05-18T12:11:50Z (GMT). No. of bitstreams: 1 468781 - Texto Parcial.pdf: 384702 bytes, checksum: cde465ffd6e2d42c31965ab814bea74f (MD5) Previous issue date: 2014-04-26 === OBJECTIVE: This paper compares the test results of DMSA renal scintigraphy performed 1, 3 and 6 hours after administration of the radiopharmaceutical in children with clinical suspicion of acute pyelonephritis. MATERIALS E METHODS: DMSA Images were performed 1, 3 and 6 h after tracer injection and evaluated by three nuclear medicine physicians, who rated the kidneys from normal and abnormal, in the three different moments. We used the Criteria for acute pyelonephritis published by The European Association of Nuclear Medicine and the Consensus of normality and its variants, proposed by 30 experts in nuclear nephrology and published in 1999. Moreover, was performed the relative renal function on each patient, for each protocol image, by counting the activity of 99m Tc-DMSA uptake in both kidneys. RESULTS: One hundred sixty nine kidneys from 88 patients were evaluated. There was agreement intra-observer and inter-observer for all comparisons. The prevalence of acute pyelonephritis was 22,7%. There were no statistically significant changes in function calculation on the three proposed protocols. CONCLUSION: There was no statistically significant difference in the images taken at 1, 3 and 6h in the scintigraphic evaluation of acute pyelonephritis in children up to ten years. Also do not change the functional indices in the three moments. === OBJETIVO: Esse trabalho compara os resultados dos exames de cintilografia renal com DMSA realizados 1, 3 e 6h ap?s a administra??o do radiof?rmaco em crian?as com suspeita cl?nica de pielonefrite aguda. MATERIAIS E M?TODOS: As imagens de DMSA foram realizadas 1, 3 e 6h ap?s a inje??o do radiof?rmaco e avaliadas por tr?s m?dicos nucleares, que classificaram os rins em normal ou anormal, nos tr?s momentos diferentes, isoladamente. Foram usados os crit?rios para pielonefrite aguda publicados pela Associa??o Europeia de Medicina Nuclear e o Consenso de normalidade e suas poss?veis variantes, proposto por 30 especialistas em nefrologia nuclear e publicado em 1999. Al?m disso, foi realizado o c?lculo da capta??o renal relativa de cada paciente, para cada protocolo de imagem, atrav?s da contagem da atividade de capta??o do 99mTc-DMSA em cada rim. RESULTADOS: foram avaliados 169 rins de 88 pacientes. Houve concord?ncias intra-observadores e inter-observadores para todas as compara??es realizadas. A preval?ncia de pielonefrite aguda foi de 22,7%. N?o houve altera??es estatisticamente significativas nos c?lculos das fun??es relativas nos tr?s protocolos propostos. CONCLUS?O: N?o h? diferen?a estatisticamente significativa nas imagens realizadas em 1, 3 e 6h na avalia??o cintilogr?fica de pielonefrite aguda em crian?as de zero a dez anos com quadro cl?nico de ITU. Tamb?m n?o variam os ?ndices funcionais nos tr?s momentos.