Metabólitos secundários como potenciais inibidores de CDK8 (proteína quinase humana)

Metabólitos secundários como potenciais inibidores de CDK8 (proteína quinase humana)

Quinases Dependentes de Ciclinas (CDKs) são holoenzimas que possuem uma subunidade catalítica, a CDK, e uma subunidade regulatória, a ciclina. CDKs são Ser/Thr quinases, ou seja, fosforilam resíduos de aminoácidos específicos. A CDK8 fosforila o CTD da RNA Pol II, sendo considerada como regulado...

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Bibliographic Details
Main Author:	Buana Carvalho de Almeida
Other Authors:	Fernanda Canduri
Language:	Portuguese
Published:	Universidade de São Paulo 2018
Subjects:	CDK clonagem expressão inibidores metabólitos quinase cloning expression inhibitors kinase metabolites
Online Access:	http://www.teses.usp.br/teses/disponiveis/75/75133/tde-25042018-142801/

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