Regulating the anterior medial prefrontal cortex : exploratory investigation of real-time fMRI training
The feasibility of using real-time functional magnetic resonance imaging (fMRI) feedback regarding the level of activation in rostromedial prefrontal cortex (rMPFC) to learn improved regulation of this brain area was examined in a group of 5 young adults. Subjects received real-time feedback from t...
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ndltd-LACETR-oai-collectionscanada.gc.ca-BVAU.-14132013-06-05T04:16:51ZRegulating the anterior medial prefrontal cortex : exploratory investigation of real-time fMRI trainingSmith, Rachelle MariefMRIEmotion regulationMedial prefrontal cortexReal-time feedbackThe feasibility of using real-time functional magnetic resonance imaging (fMRI) feedback regarding the level of activation in rostromedial prefrontal cortex (rMPFC) to learn improved regulation of this brain area was examined in a group of 5 young adults. Subjects received real-time feedback from the target brain region while engaging in a blocked-design task involving alternating blocks of attempted up-regulation and down-regulation of the target brain region. A transient negative emotional state was induced prior to each scanning session. Subjects completed 6 scanning sessions (a pre-training session, 4 feedback sessions and a post-training session - no feedback was provided for pre and post-training sessions). The guideline strategy provided to subjects of engaging in emotional awareness during up-regulation and bodily awareness during down-regulation was found to consistently regulate the region in the pre-training session prior to the fMRI feedback sessions. This finding is in line with the previously proposed role of the rMPFC in emotional awareness. In contrast to previous real-time fMRI findings, greater recruitment of the region was observed in the pre-training session compared to the post-training session, with a non-significant negative trend observed across feedback sessions. These results suggest that there may be limitations to which the feedback techniques successfully employed for other brain regions extend to yet unexplored brain regions.University of British Columbia2008-08-19T17:43:57Z2008-08-19T17:43:57Z20082008-08-19T17:43:57Z2008-11Electronic Thesis or Dissertation7014318 bytesapplication/pdfhttp://hdl.handle.net/2429/1413eng |
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Others
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fMRI Emotion regulation Medial prefrontal cortex Real-time feedback |
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fMRI Emotion regulation Medial prefrontal cortex Real-time feedback Smith, Rachelle Marie Regulating the anterior medial prefrontal cortex : exploratory investigation of real-time fMRI training |
description |
The feasibility of using real-time functional magnetic resonance imaging (fMRI) feedback regarding the level of activation in rostromedial prefrontal cortex (rMPFC) to learn improved regulation of this brain area was examined in a group of 5 young adults. Subjects received real-time feedback from the target brain region while engaging in a blocked-design task involving alternating blocks of attempted up-regulation and down-regulation of the target brain region. A transient negative emotional state was induced prior to each scanning session. Subjects completed 6 scanning sessions (a pre-training session, 4 feedback sessions and a post-training session - no feedback was provided for pre and post-training sessions). The guideline strategy provided to subjects of engaging in emotional awareness during up-regulation and bodily awareness during down-regulation was found to consistently regulate the region in the pre-training session prior to the fMRI feedback sessions. This finding is in line with the previously proposed role of the rMPFC in emotional awareness. In contrast to previous real-time fMRI findings, greater recruitment of the region was observed in the pre-training session compared to the post-training session, with a non-significant negative trend observed across feedback sessions. These results suggest that there may be limitations to which the feedback techniques successfully employed for other brain regions extend to yet unexplored brain regions. |
author |
Smith, Rachelle Marie |
author_facet |
Smith, Rachelle Marie |
author_sort |
Smith, Rachelle Marie |
title |
Regulating the anterior medial prefrontal cortex : exploratory investigation of real-time fMRI training |
title_short |
Regulating the anterior medial prefrontal cortex : exploratory investigation of real-time fMRI training |
title_full |
Regulating the anterior medial prefrontal cortex : exploratory investigation of real-time fMRI training |
title_fullStr |
Regulating the anterior medial prefrontal cortex : exploratory investigation of real-time fMRI training |
title_full_unstemmed |
Regulating the anterior medial prefrontal cortex : exploratory investigation of real-time fMRI training |
title_sort |
regulating the anterior medial prefrontal cortex : exploratory investigation of real-time fmri training |
publisher |
University of British Columbia |
publishDate |
2008 |
url |
http://hdl.handle.net/2429/1413 |
work_keys_str_mv |
AT smithrachellemarie regulatingtheanteriormedialprefrontalcortexexploratoryinvestigationofrealtimefmritraining |
_version_ |
1716586762060431360 |